General Cell Lines and Cell Cultures
ATCC Candida parapsilosis; B78
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Campylobacter helveticus
Campylobacter helveticus strain NCTC 12470 is a bacterial type strain that was isolated from a cat in Switzerland.
ATCC Fusarium verticilliodes; H66173
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
Human herpesvirus 2; Strain: ATCC-2011-2; Herpes simplex virus 2
Human herpesvirus 2 strain ATCC-2011-2 is propagated in Vero cells (ATCC CCL-81). The virus was isolated from a clinical sample from a patient positive for HSV-2 in Virginia in 2011. It has applications in infectious disease and sexually transmitted disease research.
ATCC Borrelia burgdorferi; Quantitative DNA
Quantitative genomic DNA from Borrelia burgdorferi strain B31 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load and for other molecular biology applications.
Eurofins Discoverx Ready-to-Assay NK2 Tachykinin Receptor Frozen Cells, 2 Vials of Cells. (HTS144RTA)
The Ready-to-Assay NK2 Tachykinin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. tachykinins) based activation of TACR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TACR2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of TACR2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen CXCR4 Receptor Stable Cell Line, 2 vials. (HTS004C)
The ChemiScreen CXCR4 Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL12/SDF-1α) based activation of CXCR4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CXCR4 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CXCR4, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen NTR1 Neurotensin Receptor Stable Cell Line, 2 vials. (HTS034C)
The ChemiScreen NTR1 Neurotensin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. neurotensin) based activation of NTSR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses NTSR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of NTSR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Salmonella enterica; subspecies enterica; serovar Enteritidis; Strain: SAP18-0432
Salmonella enterica subsp. enterica serovar Enteritidis strain SAP18-0432 was isolated in the United States from a human. This whole-genome sequenced bacterium was part of the 2018 PulseNet-GenomeTrakr joint proficiency test exercise. This strain has applications in infectious disease research and zoonotic disease research.
ATCC Leptospira interrogans; serovar Copenhageni; genomic DNA
Genomic DNA isolated from Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130 (ATCC BAA-1198). This whole-genome sequenced product can be used in PCR and other molecular biology applications.